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Polynucleotide acne scar treatment at Vincere Aesthetics Clinic, Singapore
Acne Scar Treatment

Polynucleotide Acne Scar Treatment

Regenerative scar repair

Polynucleotide acne scar treatment delivers regenerative DNA-fragment therapy into and around acne scar tissue to support skin repair and texture renewal — administered by Dr. Vincent as part of a tailored scar protocol.

Duration
30–45 min
Downtime
Minimal
Results
4–8 weeks
Longevity
Series-based
About the Treatment

About polynucleotide for scar repair

Polynucleotides are short fragments of purified DNA that, when injected into the skin, support the natural processes of tissue repair — including the regeneration of collagen, the recruitment of repair cells, and improved local micro-circulation. In the context of acne scarring, this matters because scar tissue is fundamentally disorganised tissue: collagen laid down hastily by the body during healing, lacking the structure of normal skin.

Polynucleotide therapy works alongside, not instead of, structural treatments. For deep boxcar or rolling scars, the combination of energy-based resurfacing or microneedling — which physically remodels the scar — with polynucleotide support for the surrounding tissue tends to produce more meaningful texture change than either approach alone.

Dr. Vincent treats acne scarring as a multi-modality concern. The polynucleotide component is particularly suited to clients whose scars have stabilised (no active acne in the area for at least several months) and who want to support tissue quality alongside more direct scar interventions.

Duration
30–45 min
Downtime
Small bumps at injection sites settle within 24–48 hours
Results
Texture improvement progresses across a series of sessions
Longevity
Cumulative — built across multiple sessions
Is This for Me?

Common scar types addressed

Rolling scars

Wave-like depressions where the skin appears uneven. Polynucleotides support the dermal tissue beneath, often used alongside subcision or energy-based resurfacing.

Boxcar scars

Sharper, well-defined depressions. Best addressed with structural treatments first, with polynucleotides supporting tissue quality and recovery between sessions.

Atrophic scars (general thinning)

Areas of skin where collagen has been lost during healing. Regenerative support helps rebuild dermal volume gradually.

Skin quality around scars

Scar areas often have surrounding skin that is dull, uneven in tone, or thinner than the rest. Polynucleotide therapy improves this background quality.

Post-active-acne stabilisation

For clients whose acne has settled and who are ready to begin scar treatment — polynucleotides can help calm the residual skin environment before more aggressive resurfacing.

Your Journey

Your treatment journey

01

Scar assessment

30 min
Dr. Vincent examines your scar pattern — type, depth, distribution — and discusses whether polynucleotide alone or in combination with other treatments will produce the most meaningful change.
02

Skin preparation

20–30 min
The treatment area is cleansed. Topical numbing is applied and given 20–30 minutes to take effect before injection.
03

Polynucleotide injection

20–30 min
Small volumes of polynucleotide solution are placed into and around scar tissue using a fine needle or micro-cannula technique. Several injection points are typically needed across an affected area.
04

Aftercare & series planning

10 min
Small bumps or mild swelling at injection sites usually settle within 24–48 hours. A series of 3–4 sessions spaced 3–4 weeks apart is common; some clients continue to a longer protocol depending on response.
Why Vincere

Why choose Vincere

Acne scarring is one of the more demanding aesthetic concerns to treat well. Results require realistic expectations and an honest conversation about which scars will respond meaningfully and which need a different approach. Dr. Vincent treats scars as a multi-step protocol — not a single procedure with a single answer.

Polynucleotide therapy fits within a broader scar protocol, often used to support tissue between or alongside more direct scar interventions like microneedling or laser resurfacing. The aim is optimal outcome with minimal downtime, without compromise — meaningful improvement without long recovery windows that disrupt daily life.

The treatment is honest about its limits. Severe, very deep scarring may need surgical excision or other approaches; polynucleotides cannot fill or remove an existing scar by themselves. Dr. Vincent will tell you what is realistic at consultation — including when polynucleotide is not the right starting point and what should be addressed first.

Thousands
Aesthetic procedures performed
3–4
Typical session count for scars
Multi
Modality scar protocol
Doctor
Personally treats every client
FAQ

Frequently asked
questions

Can't find your answer here? Message Dr. Vincent — he's happy to address your concerns personally.

For most scar types, polynucleotide is part of a combination approach rather than a standalone treatment. It supports tissue quality and regeneration, but structural scars typically also need direct intervention — microneedling, energy-based resurfacing, or subcision — to physically remodel the scar itself. Dr. Vincent will explain which combination suits your specific scar pattern.
Polynucleotide acne scar treatment typically starts with 3 to 4 sessions spaced 3 to 4 weeks apart. Some clients continue to a longer protocol of 6 or more sessions depending on the scar severity and how the tissue is responding. The plan is reviewed throughout, not fixed at the start.
Polynucleotide acne scar downtime is minimal. Small bumps or mild swelling at the injection points are common and typically settle within 24 to 48 hours. Some bruising can occur. Most clients return to work the next day, though a visible appointment or social plan within the first 24 hours is best avoided.
Skin boosters primarily hydrate and support general skin quality with hyaluronic acid. Polynucleotides act on the cellular and tissue level — they are regenerative rather than primarily hydrating. The two are different tools for different goals; in scar work, polynucleotide is more directly relevant.
Active acne in the treatment area should generally be settled for at least several months before scar work begins, otherwise new acne lesions can form new scars even as old ones are being treated. Dr. Vincent will assess whether your skin is ready at consultation.
The improvements to scar tissue and surrounding skin are durable — once tissue is regenerated, it does not undo itself. Skin continues to age normally, however, so periodic maintenance sessions help preserve and extend results over time.
Yes. Polynucleotide injections do not use heat or laser energy, so the risk of pigmentation changes seen with some scar treatments is not a concern here. This makes it a particularly useful option for clients with deeper skin tones for whom certain laser-based scar treatments require more cautious settings.
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